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CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS) smoldering myeloma MM and PC leukemia CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56 Most importantly CD229 was also highly expressed on those cells in the patients BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells
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Medchemexpress, HY-K0021 1 mL Phosphatase Inhibitor Cocktail I (100X in DMSO) CAS: Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress, HY-K0206 1 mL Anti-c-Myc Magnetic Beads CAS: Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress, HY-K0203 5 mL Protein A Magnetic Beads CAS: Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress, HY-K0030 1 mL Deacetylase Inhibitor Cocktail (100× in 70% DMSO) CAS: Deacetylase Inhibitor Cocktail is a synergistic combination of chemicals designed to preserve the acetylation state of proteins. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress, HY-K0208 5 mL Streptavidin Magnetic Beads CAS: Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 uM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of some compounds to receive electrons. purity: 97%
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A GPX4 inhibitor and ferroptosis inducer; inhibits GPX4 activity by 49.16% at 1 µM; increases the production of ROS and levels of MDA in OS-RC-2 cells 0.5 µM; induces ferroptosis in HT-1080 cells (IC50s = 0.007 and 1.486 µM, in the absence and presence of ferrostatin-1, respectively); reduces tumor volume and intratumoral GPX4 levels in an OS-RC-2 mouse xenograft model 20 mg/kg
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